Predictors of Pathologic Complete Response Following Neoadjuvant Chemoradiotherapy for Rectal Cancer

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Clinical parameters predicting pathologic complete response following neoadjuvant chemoradiotherapy for rectal cancer.

INTRODUCTION Preoperative chemoradiotherapy (CRT), followed by total mesorectal excision, has become the standard of care for patients with clinical stages II and III rectal cancer. Patients with pathologic complete response (pCR) to preoperative CRT have been reported to have better outcomes than those without pCR. However, the factors that predict the response to neoadjuvant CRT have not been...

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Predictors of pathologic complete response after preoperative concurrent chemoradiotherapy of rectal cancer: a single center experience

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Comparison of 5FU-base Chemoradiation with and without Eloxatin on Pathologic Complete Response in Neoadjuvant Chemoradiation of Rectal cancer

  Background and Objectives: To compare pathologic complete response (pCR) in patients with advanced rectal cancer receiving neoadjuvant chemoradiotherapy (NACT) by 5-FU or Xeloda (capecitabine) with and without Eloxatin (oxaloplatin injection). Materials and Methods: Seventy-five consecutive patients with the diagnosis of advanced rectal adenocarcinoma were included. Two basic chemotherapy r...

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Morphologic predictors of pathological complete response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer

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ژورنال

عنوان ژورنال: Annals of Surgical Oncology

سال: 2015

ISSN: 1068-9265,1534-4681

DOI: 10.1245/s10434-015-5017-y